Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536906 | 0.97 | THRB (0.42) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL11536932 | 0.97 | THRB (0.48) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL11538522 | 0.94 | THRB (0.43) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL28234072 | 0.91 | THRB (0.39) | THRB | |
| SCHEMBL11542038 | 0.86 | THRB (0.42) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL15016766 | 0.82 | THRB (0.38) | THRB | |
| SCHEMBL10421655 | 0.78 | THRB (0.59) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL7647628 | 0.78 | THRB (0.59) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL5692331 | 0.77 | LMNA (0.45) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL11204685 | 0.74 | THRB (0.48) | THRBLMNACA2CA1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1034204-B1 | ROOM TEMPERATURE CURABLE SILANE TERMINATED AND STABLE WATERBORNE POLYURETHANE DISPERSIONS WHICH CONTAIN FLUORINE AND/OR SILICONE AND LOW SURFACE ENERGY COATINGS PREPARED THEREFROM | MINNESOTA MINING & MFG (US) | 2004-02-11 | — | — | EP | disclosed |
| US-6313335-B1 | Room temperature curable silane terminated and stable waterborne polyurethane dispersions which contain fluorine and/or silicone and low surface energy coatings prepared therefrom | 3M INNOVATIVE PROPERTIES | 2001-11-06 | — | — | US | disclosed |
| EP-1034204-A1 | ROOM TEMPERATURE CURABLE SILANE TERMINATED AND STABLE WATERBORNE POLYURETHANE DISPERSIONS WHICH CONTAIN FLUORINE AND/OR SILICONE AND LOW SURFACE ENERGY COATINGS PREPARED THEREFROM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999026992-A1 | ROOM TEMPERATURE CURABLE SILANE TERMINATED AND STABLE WATERBORNE POLYURETHANE DISPERSIONS WHICH CONTAIN FLUORINE AND/OR SILICONE AND LOW SURFACE ENERGY COATINGS PREPARED THEREFROM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |