Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520767 | 0.83 | ADRB2 (0.50) | — | |
| SCHEMBL13851783 | 0.72 | CTSA (0.51) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL18162818 | 0.72 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1 | |
| SCHEMBL4596498 | 0.71 | MAPK1 (0.51) | MEN1KMT2A | |
| SCHEMBL3446408 | 0.71 | MAPK1 (0.51) | MEN1KMT2A | |
| SCHEMBL29751787 | 0.71 | MAPK1 (0.46) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL16901655 | 0.71 | MAPK1 (0.46) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL31037006 | 0.71 | MAPK1 (0.46) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL14107607 | 0.71 | IDO1 (0.46) | MEN1KMT2A | |
| SCHEMBL14393701 | 0.70 | MAPK1 (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156739-A | B-HYDROXYAMINO-HYDROCINNAMONYLHYDROXAMIC ACIDS | RESEARCH CORPORATION (US) | 1979-05-29 | — | — | US | disclosed |
| US-4098903-A | ANTI-HYPERTENSIVE COMPOUNDS | RESEARCH CORPORATION (US) | 1978-07-04 | — | — | US | disclosed |
| US-4083864-A | ANTIHYPERTENSIVE AGENTS | RESEARCH CORPORATION (US) | 1978-04-11 | — | — | US | disclosed |