Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 2/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464005 | 0.87 | CYP3A4 (0.62) | CYP3A4HPGDMEN1ALOX15KMT2A | |
| SCHEMBL979351 | 0.87 | HPGD (0.62) | CYP3A4HPGDMEN1ALOX15KMT2A | |
| SCHEMBL28838076 | 0.84 | MEN1 (0.58) | CYP3A4HPGDMEN1ALOX15KMT2A | |
| SCHEMBL7584267 | 0.77 | MEN1 (0.58) | CYP3A4HPGDMEN1ALOX15KMT2A | |
| SCHEMBL6441850 | 0.75 | PTPN1 (0.62) | ALOX15PTPN1PTPN2PTPN6BCL2 | |
| SCHEMBL13316485 | 0.74 | CYP3A4 (0.54) | CYP3A4HPGDMEN1ALOX15KMT2A | |
| Clorophene SCHEMBL78119 | 0.74 | HIF1A (1.00) | CYP3A4HPGDMEN1ALOX15KMT2A | |
| SCHEMBL5004345 | 0.74 | MEN1 (0.62) | CYP3A4HPGDMEN1ALOX15KMT2A | |
| Clorophene SCHEMBL29377427 | 0.74 | HIF1A (1.00) | CYP3A4HPGDMEN1ALOX15KMT2A | |
| SCHEMBL11541896 | 0.73 | ALDH1A1 (0.57) | CYP3A4HPGDMEN1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167632-A | APPETITE SUPPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1979-09-11 | — | — | US | disclosed |