Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.62 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.62 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HNF4A | P41235 | 1/20 | 0.56 |
| ▸ | BCL2 | P10415 | 2/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.52 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442120 | 0.94 | PTPN1 (0.61) | PTPN1PTPN2PTPN6TSHRHNF4A | |
| SCHEMBL27415949 | 0.85 | PTPN1 (0.53) | PTPN1PTPN2PTPN6TSHRHNF4A | |
| SCHEMBL8961442 | 0.84 | PTPN1 (0.65) | PTPN1PTPN2PTPN6TSHRHNF4A | |
| SCHEMBL6772376 | 0.84 | TSHR (0.69) | PTPN1PTPN2PTPN6TSHRHNF4A | |
| SCHEMBL4521739 | 0.83 | TSHR (0.72) | PTPN1PTPN2PTPN6TSHRHNF4A | |
| SCHEMBL11555259 | 0.83 | IDO1 (0.55) | PTPN1PTPN2PTPN6TSHRHNF4A | |
| SCHEMBL310681 | 0.83 | PTPN1 (0.58) | PTPN1PTPN2PTPN6TSHRHNF4A | |
| SCHEMBL28707306 | 0.83 | PTPN1 (0.73) | PTPN1PTPN2PTPN6TSHRHNF4A | |
| SCHEMBL23003 | 0.83 | TSHR (0.79) | PTPN1PTPN2PTPN6TSHRHNF4A | |
| SCHEMBL11590733 | 0.82 | PTPN1 (0.50) | PTPN1PTPN2PTPN6TSHRHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288522-A1 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY | 2005-12-29 | — | — | US | claimed |
| CN-1592729-A | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES CO (US) | 2005-03-09 | — | — | CN | claimed |
| US-20030100779-A1 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-29 | — | — | US | claimed |
| US-20030097010-A1 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-22 | — | — | US | claimed |
| US-20050288522-A1 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY | 2005-12-29 | — | — | US | disclosed |
| US-6974877-B2 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-12-13 | — | — | US | disclosed |
| CN-1592729-A | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES CO (US) | 2005-03-09 | — | — | CN | disclosed |
| EP-1430008-A2 | PROCESS FOR PREPARING PENTACENE DERIVATIVES | 3M Innovative Properties Company (US) | 2004-06-23 | — | — | EP | disclosed |
| US-20030100779-A1 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-29 | — | — | US | disclosed |
| US-20030097010-A1 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-22 | — | — | US | disclosed |
| WO-2003027050-A2 | PROCESS FOR PREPARING PENTACENE DERIVATIVES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288522-A1 | Process for preparing pentacene derivatives | RARA, RARB, C9 | PTPN1 1890/4885PTPN2 2127/4885PTPN6 2123/4885 |
| US-20030097010-A1 | Process for preparing pentacene derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PCBP1, RARA | PTPN1 2512/4885PTPN2 2891/4885PTPN6 2603/4885 |
| US-20030100779-A1 | Process for preparing pentacene derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PCBP1, RARA | PTPN1 2512/4885PTPN2 2891/4885PTPN6 2603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.