Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11572694 | 0.94 | LPAR3 (0.42) | LPAR3LPAR2LPAR1ALDH1A1CYP3A4 | |
| SCHEMBL11124800 | 0.90 | LPAR3 (0.44) | LPAR3LPAR2LPAR1ALDH1A1CYP3A4 | |
| Dimethylamine SCHEMBL10905577 | 0.89 | LPAR2 (0.38) | LPAR3LPAR2LPAR1ALDH1A1CYP3A4 | |
| SCHEMBL8469570 | 0.89 | LPAR3 (0.47) | LPAR3LPAR2LPAR1 | |
| SCHEMBL11694818 | 0.89 | LPAR3 (0.47) | LPAR3LPAR2LPAR1 | |
| Dimethylamine SCHEMBL10894336 | 0.85 | LPAR3 (0.40) | LPAR3LPAR2LPAR1ALDH1A1CYP3A4 | |
| SCHEMBL4604619 | 0.84 | ALDH1A1 (0.41) | LPAR3LPAR2ALDH1A1CYP3A4HSD17B10 | |
| Potassium SCHEMBL11442510 | 0.82 | ALDH1A1 (0.39) | LPAR3LPAR2ALDH1A1CYP3A4HSD17B10 | |
| Hydrochloric Acid SCHEMBL8983797 | 0.82 | ALDH1A1 (0.39) | LPAR3LPAR2ALDH1A1CYP3A4HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL11610686 | 0.82 | ALDH1A1 (0.39) | LPAR3LPAR2ALDH1A1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137065-A | HERBICIDE, INSECTICIDE, NEMATOCIDE, MITICIDE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1979-01-30 | — | — | US | disclosed |