SCHEMBL11537607

SCHEMBL11537607

C=C(C)CC(CC(=C)C)C(=O)C1C2CCC(C2)C1(C)C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RET P07949 1/20 0.30
MAPK14 Q16539 1/20 0.30
CAMK1D Q8IU85 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11532216 0.76 ALDH1A1 (0.31)
SCHEMBL453690 0.73 NPSR1 (0.33) RETMAPK14CAMK1D
SCHEMBL11534412 0.71 ALDH1A1 (0.31)
SCHEMBL6551752 0.70 ALDH1A1 (0.33) RETMAPK14CAMK1D
SCHEMBL7552292 0.70 ALDH1A1 (0.34)
SCHEMBL7548127 0.69 ALDH1A1 (0.30)
SCHEMBL5129829 0.68 ALDH1A1 (0.33)
SCHEMBL11532938 0.68 ALDH1A1 (0.34)
SCHEMBL10943675 0.68 ALDH1A1 (0.34)
SCHEMBL7545028 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4153811-A ORGANOLEPTIC INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-05-08 US disclosed
US-4153568-A Process of enhancing the aroma of a soap with norbornane derivatives INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-05-08 US disclosed
US-4151309-A FOODS, CHEWING GUM, DENTIFRICES, DRUGS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-04-24 US disclosed
US-4148826-A PERFUMES, FLAVORS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-04-10 US disclosed
US-4143074-A ORGANOLEPTIC INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-03-06 US disclosed
US-4136120-A GRIGNARD REACTION, CHELATION, HYDROLYSIS, DEHYDRATION INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-01-23 US disclosed
US-4136208-A FLAVORING WITH SUBSTITUTED NORBORNANE DERIVATIVES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-01-23 US disclosed
US-4130587-A ORGANOLEPTIC INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-12-19 US disclosed
US-4126569-A Process of enhancing the aroma of a soap with liquid detergent norbornane derivatives INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-11-21 US disclosed
US-4126571-A Process of enhancing the aroma of a soap with norbornane derivatives INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-11-21 US disclosed
US-4126570-A Process of enhancing the aroma of a detergent with norbornane derivatives INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-11-21 US disclosed
US-4123393-A Substituted-norbornane perfume compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-10-31 US disclosed
US-4120308-A Substituted norbornane derivatives used in the process of flavoring tobacco and the product thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-10-17 US disclosed
US-4119577-A Substituted-norbornane perfumes compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-10-10 US disclosed
US-4076853-A Flavoring with substituted norbornane derivatives INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-02-28 US disclosed