SCHEMBL453690

SCHEMBL453690

CC(=O)C1C2CCC(C2)C1(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.33
ALDH1A1 P00352 1/20 0.33
RET P07949 1/20 0.31
MAPK14 Q16539 1/20 0.31
CAMK1D Q8IU85 1/20 0.31
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
G6PD P11413 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30
GABRG2 P18507 2/20 0.30
GABRB3 P28472 2/20 0.30
GABRA5 P31644 2/20 0.30
GABRA3 P34903 2/20 0.30
GABRA2 P47869 2/20 0.30
GABRB2 P47870 2/20 0.30
GABRA4 P48169 2/20 0.30
GABRE P78334 2/20 0.30
GABRA6 Q16445 2/20 0.30
GABRG1 Q8N1C3 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551752 0.83 ALDH1A1 (0.33) NPSR1ALDH1A1RETMAPK14CAMK1D
SCHEMBL195829 0.79 CHRNB2 (0.35) NPSR1ALDH1A1CYP3A4MEN1KMT2A
SCHEMBL10937317 0.76 ALDH1A1 (0.33) NPSR1ALDH1A1
SCHEMBL11532435 0.76 ALDH1A1 (0.33) NPSR1ALDH1A1RETMAPK14CAMK1D
SCHEMBL10937315 0.76 ALDH1A1 (0.33) NPSR1ALDH1A1
SCHEMBL11536857 0.76 ALDH1A1 (0.33) NPSR1ALDH1A1
SCHEMBL11532216 0.76 ALDH1A1 (0.31) NPSR1ALDH1A1
SCHEMBL6408630 0.75
SCHEMBL8509016 0.75 ALDH1A1 (0.37) ALDH1A1
SCHEMBL11537607 0.73 RET (0.30) RETMAPK14CAMK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 888 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325463-A1 COMPOSITIONS (III) SYMRISE AG (DE) 2025-10-23 US claimed
US-12398341-B2 Apparatus and compositions for improving scent delivery THE PROCTER & GAMBLE COMPANY (US) 2025-08-26 US claimed
CN-119968452-A Perfume mixture (VI) 西姆莱斯股份公司 2025-05-09 CN claimed
EP-4532646-A1 A FRAGRANCE MIXTURE (V) Symrise AG (DE) 2025-04-09 EP claimed
CN-119790128-A Perfume mixture (III) 西姆莱斯股份公司 2025-04-08 CN claimed
US-20250099349-A1 A FRAGRANCE MIXTURE SYMRISE AG (DE) 2025-03-27 US claimed
US-12247180-B2 Apparatus and compositions for improving scent delivery THE PROCTER & GAMBLE COMPANY (US) 2025-03-11 US claimed
CN-119317696-A Perfume mixture (V) 西姆莱斯股份公司 2025-01-14 CN claimed
CN-119317695-A Perfume mixture (V) 西姆莱斯股份公司 2025-01-14 CN claimed
EP-4472606-A1 COMPOSITIONS (III) Symrise AG (DE) 2024-12-11 EP claimed
WO-2012084292-A1 PERFUME COMPOSITION COMPRISING FRAGRANCE ALDEHYDE OR KETONE AND OXAZOLIDINE FRAGRANCE PRECURSOR HENKEL AG & CO. KGAA (DE) 2012-06-28 WO claimed
EP-2440643-A1 ODOR-IMPARTING DETERGENT, CLEANING OR CARE PRODUCT Henkel AG & Co. KGaA (DE) 2012-04-18 EP claimed
US-20110237685-A1 PHOTOLABILE FRAGRANCE STORAGE SUBSTANCES HENKEL AG & CO. KGAA (DE) 2011-09-29 US claimed
WO-2011101182-A1 STABILIZED PERFUME OILS HENKEL AG & CO. KGAA (DE) 2011-08-25 WO claimed
WO-2010142481-A1 ODOR-IMPARTING DETERGENT, CLEANING OR CARE PRODUCT HENKEL AG & CO. KGAA (DE) 2010-12-16 WO claimed
EP-2227233-A2 IDO INHIBITORS Newlink Genetics (US) 2010-09-15 EP claimed
WO-2009073620-A2 IDO INHIBITORS NEWLINK GENETICS (US) 2009-06-11 WO claimed
EP-1848702-A2 PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS Flexitral, Inc. (US) 2007-10-31 EP claimed
US-20060205632-A1 Pro-fragrance and pro-flavorant compositions FLEXITRAL, INC. 2006-09-14 US claimed
WO-2006085048-A2 PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS FLEXITRAL, INC. (US) 2006-08-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237685-A1 PHOTOLABILE FRAGRANCE STORAGE SUBSTANCES TRPA1, NISCH, ALDH18A1 NPSR1 197/4885ALDH1A1 12/4885RET 3465/4885
US-20250099349-A1 A FRAGRANCE MIXTURE PTMS, EP300, TRPA1 NPSR1 681/4885ALDH1A1 967/4885RET 3697/4885
US-20060205632-A1 Pro-fragrance and pro-flavorant compositions TAS2R10, TAS2R9, OR10J3 NPSR1 259/4885ALDH1A1 1201/4885RET 911/4885
US-20250325463-A1 COMPOSITIONS (III) NISCH, TAS1R3, TAS2R3 NPSR1 1809/4885ALDH1A1 1377/4885RET 4328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.