Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | PORCN | Q9H237 | 3/20 | 0.47 |
| ▸ | RAF1 | P04049 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | IDH2 | P48735 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541657 | 0.90 | MEN1 (0.76) | MEN1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL11540166 | 0.85 | KMT2A (0.60) | MEN1KMT2AMAPTCYP3A4CA12 | |
| SCHEMBL11538807 | 0.84 | KMT2A (0.67) | MEN1KMT2ALMNAMAPTCYP3A4 | |
| SCHEMBL11539010 | 0.84 | KMT2A (0.67) | MEN1KMT2AMAPTCYP3A4CYP2D6 | |
| SCHEMBL11535044 | 0.84 | MEN1 (0.78) | MEN1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL11537127 | 0.84 | MEN1 (0.67) | MEN1KMT2ACYP3A4PORCNIDO1 | |
| SCHEMBL11536044 | 0.83 | KMT2A (0.58) | MEN1KMT2ALMNAMAPTCYP3A4 | |
| SCHEMBL11536064 | 0.82 | KMT2A (0.65) | MEN1KMT2AMAPTCYP3A4IDO1 | |
| SCHEMBL11472293 | 0.82 | MEN1 (0.71) | MEN1KMT2AMAPTNPSR1CYP3A4 | |
| SCHEMBL11537785 | 0.82 | MEN1 (0.71) | MEN1KMT2ALMNAMAPTRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160097-A | INTERMEDIATES FOR FUNGICIDAL AND ANTIINFLAMMATORY 4-SUBSTITUTED IMIDAZO(1,2-A)QUINOXALINES | WESTWIND PHARMACEUTICALS, INC. (US) | 1979-07-03 | — | — | US | claimed |