Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | IDH2 | P48735 | 1/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541657 | 0.91 | MEN1 (0.76) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11537220 | 0.88 | MEN1 (0.76) | KMT2AMEN1CYP3A4IDO1IDH2 | |
| SCHEMBL11537127 | 0.87 | MEN1 (0.67) | KMT2AMEN1CYP3A4IDO1IDH2 | |
| SCHEMBL11535044 | 0.87 | MEN1 (0.78) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11539010 | 0.87 | KMT2A (0.67) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11541067 | 0.87 | MEN1 (0.63) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11536064 | 0.85 | KMT2A (0.65) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11464531 | 0.85 | CYP3A4 (0.55) | KMT2AMEN1LMNAMAOBCYP3A4 | |
| SCHEMBL11537243 | 0.84 | KMT2A (0.67) | KMT2AMEN1NPC1RAB9ACYP3A4 | |
| SCHEMBL11538004 | 0.84 | MEN1 (0.64) | KMT2AMEN1MAPTLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160097-A | INTERMEDIATES FOR FUNGICIDAL AND ANTIINFLAMMATORY 4-SUBSTITUTED IMIDAZO(1,2-A)QUINOXALINES | WESTWIND PHARMACEUTICALS, INC. (US) | 1979-07-03 | — | — | US | claimed |