Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MFN2 | O95140 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535866 | 0.90 | MGLL (0.32) | MGLLBCHEMEN1KMT2ASLC18A3 | |
| SCHEMBL11711234 | 0.90 | MGLL (0.32) | MGLLBCHEMEN1KMT2ASLC18A3 | |
| SCHEMBL11709610 | 0.90 | GRM2 (0.38) | MEN1KMT2ALMNA | |
| SCHEMBL11738059 | 0.87 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL11747240 | 0.84 | MGLL (0.32) | MGLLMEN1KMT2ALMNASLC18A3 | |
| SCHEMBL11701555 | 0.84 | MGLL (0.32) | MGLLMEN1KMT2ALMNASLC18A3 | |
| SCHEMBL11032068 | 0.80 | PPARD (0.40) | MEN1KMT2ALMNA | |
| SCHEMBL11148517 | 0.79 | SLC18A3 (0.34) | MGLLMEN1KMT2ALMNAMFN2 | |
| SCHEMBL11709167 | 0.78 | GRM2 (0.32) | — | |
| SCHEMBL11033435 | 0.78 | MEN1 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154949-A | HYPOTENSIVE AGENTS | PFIZER INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4035360-A | TISSUE SPECIFICITY, CRYSTALLINE | PFIZER INC. (US) | 1977-07-12 | — | — | US | disclosed |
| US-3932389-A | ANTIULCER AGENTS | PFIZER INC. (US) | 1976-01-13 | — | — | US | disclosed |