Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.32 |
| ▸ | PTGFR | P43088 | 3/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535562 | 0.88 | GRIK2 (0.30) | GRIK2 | |
| SCHEMBL11720913 | 0.79 | MFN2 (0.38) | GRM2GRM3 | |
| SCHEMBL11538143 | 0.78 | MGLL (0.34) | — | |
| SCHEMBL11535224 | 0.78 | GRIK1 (0.37) | GRM2GRM3PTGFRPTGER3SLCO2A1 | |
| SCHEMBL11709610 | 0.72 | GRM2 (0.38) | GRM2GRM3GRIK2 | |
| SCHEMBL11721380 | 0.72 | TBXAS1 (0.39) | GRM2GRM3PTGFRPTGER3SLCO2A1 | |
| SCHEMBL8947577 | 0.71 | — | — | |
| SCHEMBL8947910 | 0.71 | RAB9A (0.33) | — | |
| SCHEMBL8947911 | 0.71 | RAB9A (0.33) | — | |
| SCHEMBL11535866 | 0.69 | MGLL (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035360-A | TISSUE SPECIFICITY, CRYSTALLINE | PFIZER INC. (US) | 1977-07-12 | — | — | US | disclosed |
| US-3932389-A | ANTIULCER AGENTS | PFIZER INC. (US) | 1976-01-13 | — | — | US | disclosed |