Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538285 | 0.95 | MEN1 (0.49) | MEN1KMT2ATSHRCNR2CTSS | |
| SCHEMBL20528149 | 0.81 | MEN1 (0.57) | MEN1KMT2ATSHRHCAR2NAAA | |
| SCHEMBL11034348 | 0.81 | NAAA (0.47) | TSHRHCAR2NAAA | |
| SCHEMBL20528145 | 0.80 | MEN1 (0.55) | MEN1KMT2ATSHRHCAR2NAAA | |
| SCHEMBL10033529 | 0.80 | MEN1 (0.42) | MEN1KMT2ATSHRCNR2NAAA | |
| SCHEMBL29290505 | 0.80 | — | — | |
| SCHEMBL11540502 | 0.80 | NAAA (0.50) | TSHRHCAR2NAAA | |
| SCHEMBL9815160 | 0.80 | NAAA (0.50) | TSHRHCAR2NAAA | |
| SCHEMBL7687966 | 0.80 | NAAA (0.50) | TSHRHCAR2NAAA | |
| SCHEMBL9472810 | 0.80 | NAAA (0.50) | TSHRHCAR2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174428-A | CYCLIC TETRAAMINES WITH PENDANT AMINOALKYLS AND POLYSTYRENE WITH THE TETRAAMINE BONDED THERETO | Tabushi, Iwao (JP) | 1979-11-13 | — | — | US | disclosed |