Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540502 | 0.98 | NAAA (0.50) | NAAAHCAR2EPHX1TSHRALDH1A1 | |
| SCHEMBL9472810 | 0.98 | NAAA (0.50) | NAAAHCAR2EPHX1TSHRALDH1A1 | |
| SCHEMBL9815160 | 0.98 | NAAA (0.50) | NAAAHCAR2EPHX1TSHRALDH1A1 | |
| SCHEMBL7681803 | 0.98 | NAAA (0.50) | NAAAHCAR2EPHX1TSHRALDH1A1 | |
| SCHEMBL7687966 | 0.98 | NAAA (0.50) | NAAAHCAR2EPHX1TSHRALDH1A1 | |
| SCHEMBL455718 | 0.94 | ALDH1A1 (0.48) | NAAAHCAR2EPHX1TSHRALDH1A1 | |
| SCHEMBL7682195 | 0.90 | NAAA (0.52) | NAAAHCAR2EPHX1TSHRALDH1A1 | |
| SCHEMBL7681788 | 0.88 | NAAA (0.55) | NAAAHCAR2EPHX1TSHRALDH1A1 | |
| SCHEMBL7681798 | 0.88 | NAAA (0.55) | NAAAHCAR2EPHX1TSHRALDH1A1 | |
| SCHEMBL7687964 | 0.88 | NAAA (0.55) | NAAAHCAR2EPHX1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496492-A | Substituted phenylalkyl compounds | THE UPJOHN COMPANY (US) | 1985-01-29 | — | — | US | disclosed |
| US-4431820-A | BACTERICIDES; ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |
| US-4424365-A | 1,2,8,8a-Cyclopropa c!benzo 1,2,-b:-4,3-b'!dipyrrol-4(5H)-ones | THE UPJOHN COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
| US-4423228-A | CYCLIZATION OF ALCOHOL, TRIPHENYLPHOSPHINE, CARBON TETRAHALIDE | THE UPJOHN COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4423229-A | Composition of matter and process | THE UPJOHN COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4423230-A | REACTING A 5-HYDROXY BENZO(1,2-B: 3,4-B')DIPYRROLE WITH TRIPHENYLPHOSPHINE AND CARBONTETRAHALIDE OR N-IODOSUCCINIMIDE | THE UPJOHN COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4413132-A | Antibiotic CC-1065 indoline intermediates | THE UPJOHN COMPANY (US) | 1983-11-01 | — | — | US | disclosed |
| US-4400518-A | Composition of matter and process | THE UPJOHN COMPANY (US) | 1983-08-23 | — | — | US | disclosed |