Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 8/20 | 0.49 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11538844 | 0.99 | KMT2A (0.52) | KMT2AMEN1DRD4DRD2DRD3 | |
| SCHEMBL11499199 | 0.87 | DRD4 (0.53) | DRD4DRD2DRD3L3MBTL1PRMT5 | |
| SCHEMBL11538680 | 0.87 | KMT2A (0.50) | KMT2AMEN1DRD4DRD2DRD3 | |
| SCHEMBL11538412 | 0.86 | KMT2A (0.51) | KMT2AMEN1DRD4DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL11538853 | 0.85 | KMT2A (0.52) | KMT2AMEN1DRD4DRD2DRD3 | |
| Ether SCHEMBL11596436 | 0.81 | HTR1A (0.48) | KMT2AMEN1DRD4DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL11544129 | 0.80 | KMT2A (0.56) | KMT2AMEN1DRD4DRD2DRD3 | |
| SCHEMBL11537076 | 0.78 | DRD4 (0.53) | DRD4DRD2DRD3GAAL3MBTL1 | |
| SCHEMBL11543042 | 0.76 | HTR1A (0.62) | DRD4DRD2LMNA | |
| SCHEMBL11538737 | 0.76 | MEN1 (0.56) | KMT2AMEN1DRD4DRD2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146630-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-27 | — | — | US | disclosed |