Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499199 | 0.89 | DRD4 (0.53) | ADRB2ADRB1ADRB3DRD4DRD2 | |
| SCHEMBL11538745 | 0.85 | MEN1 (0.56) | MEN1KMT2AUSP2HTTATM | |
| SCHEMBL11538452 | 0.79 | TP53 (0.37) | HTTADRB2ADRB1ADRB3MAPT | |
| Hydrochloric Acid SCHEMBL11542328 | 0.79 | KMT2A (0.61) | MEN1KMT2AUSP2HTTATM | |
| SCHEMBL11538407 | 0.76 | KMT2A (0.51) | MEN1KMT2AATMDRD4DRD2 | |
| Hydrochloric Acid SCHEMBL11538844 | 0.76 | KMT2A (0.52) | MEN1KMT2ADRD4DRD2 | |
| SCHEMBL11574132 | 0.75 | ADRB1 (0.49) | MEN1KMT2AUSP2ADRB2ADRB1 | |
| SCHEMBL11537149 | 0.75 | DRD4 (0.52) | ADRB2ADRB1ADRB3DRD4DRD2 | |
| Hydrochloric Acid SCHEMBL11538648 | 0.74 | L3MBTL1 (0.51) | KMT2AADRB2ADRB1ADRB3DRD4 | |
| SCHEMBL11537076 | 0.74 | DRD4 (0.53) | ADRB2ADRB1ADRB3DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146630-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-27 | — | — | US | disclosed |