Biphenyl

Biphenyl

SCHEMBL1153864

CC#N.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
CYP1A2 P05177 2/20 0.52
CYP1A1 P04798 1/20 0.52
CYP1B1 Q16678 1/20 0.52
HSD17B10 Q99714 2/20 0.50
CYP3A4 P08684 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
SLC22A2 O15244 1/20 0.46
SLC22A1 O15245 1/20 0.46
SLC22A3 O75751 1/20 0.46
SLC6A4 P31645 1/20 0.46
TSHR P16473 1/20 0.45
MAOA P21397 1/20 0.43
NOTUM Q6P988 2/20 0.43
MAPK1 P28482 1/20 0.43
MMP3 P08254 1/20 0.43
BCL2L1 Q07817 1/20 0.43
KDM4E B2RXH2 2/20 0.41
GLA P06280 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28931658 1.00 ALDH1A1 (0.60) ALDH1A1CYP1A2CYP1A1CYP1B1HSD17B10
Biphenyl SCHEMBL29145978 1.00 ALDH1A1 (0.60) ALDH1A1CYP1A2CYP1A1CYP1B1HSD17B10
Acetonitrile SCHEMBL28399812 0.84 MMP3 (0.71) CYP1A2CYP1A1CYP1B1TDP1MMP3
Biphenyl SCHEMBL27604303 0.83 ALDH1A1 (0.64) ALDH1A1CYP1A2CYP1A1CYP1B1HSD17B10
Biphenyl SCHEMBL20530383 0.83 ALDH1A1 (0.64) ALDH1A1CYP1A2CYP1A1CYP1B1HSD17B10
Acetonitrile SCHEMBL6565616 0.82
Biphenyl SCHEMBL27842187 0.82 ALDH1A1 (0.90) ALDH1A1CYP1A2HSD17B10CYP3A4TAAR1
Biphenyl SCHEMBL27966871 0.82 ALDH1A1 (0.90) ALDH1A1CYP1A2HSD17B10CYP3A4TAAR1
Biphenyl SCHEMBL51203 0.82 ALDH1A1 (0.90) ALDH1A1CYP1A2HSD17B10CYP3A4TAAR1
Biphenyl SCHEMBL27907683 0.82 ALDH1A1 (0.90) ALDH1A1CYP1A2HSD17B10CYP3A4TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271580-B Anion exchange membrane prepared from aryl piperidine copolymer containing triazine ring branched structure, preparation method and application 大连理工大学 2024-08-16 CN claimed
CN-118271580-A Anion exchange membrane prepared from aryl piperidine copolymer containing triazine ring branched structure, preparation method and application 大连理工大学 2024-07-02 CN claimed
CN-111154499-B Chiral luminescent liquid crystal polymer with circularly polarized luminescent property and preparation method thereof 湘潭大学 2024-05-03 CN claimed
CN-117434165-A Method for detecting felbinac related substances 河北以岭医药研究院有限公司 2024-01-23 CN claimed
CN-116283783-A Preparation method of imidafenacin 南京联智医药科技有限公司 2023-06-23 CN claimed
CN-115109054-B Preparation method and application of color-changing material with multiple stimulus responses 湖州学院 2023-05-05 CN claimed
CN-115109054-A Preparation method and application of color-changing material with multiple stimulus responses 湖州学院 2022-09-27 CN claimed
CN-111171202-B Side chain type chiral luminescent liquid crystal polymer and preparation method thereof 湘潭大学 2022-02-11 CN claimed
CN-111187374-B Luminescent liquid crystal polymer containing menthol chiral structure and preparation method thereof 湘潭大学 2022-02-08 CN claimed
CN-111187374-A Luminescent liquid crystal polymer containing menthol chiral structure and preparation method thereof 湘潭大学 2020-05-22 CN claimed
CN-111171202-A Side chain type chiral luminescent liquid crystal polymer and preparation method thereof 湘潭大学 2020-05-19 CN claimed
CN-111154499-A Chiral luminescent liquid crystal polymer with circular polarization luminescent property and preparation method thereof 湘潭大学 2020-05-15 CN claimed
CN-109438512-A The preparation method of a kind of aromatic alkyl phosphorous oxide type compound 湖南大学 2019-03-08 CN claimed
CN-103086875-A Synthetic method of felbinac non-steroidal anti-inflammatory agent SHANDONG INST PHARMACEUTICAL INDUSTRY 2013-05-08 CN claimed
EP-2109601-A2 PREPARATION OF DARIFENACIN AND ITS SALTS Dr. Reddy's Laboratories Ltd. (IN) 2009-10-21 EP claimed
WO-2009125430-A2 IMPROVED PROCESS FOR PRODUCING DARIFENACIN MATRIX LABORATOIRES LIMITED (IN) 2009-10-15 WO claimed
WO-2008126106-A2 NOVEL AND IMPROVED PROCESSES FOR THE PREPARATION OF INTERMEDIATES OF DARIFENACIN, DARIFENACIN AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS SATYANARAYANA REDDY MANNE (IN) 2008-10-23 WO claimed
WO-2008100651-A2 PREPARATION OF DARIFENACIN AND ITS SALTS DR. REDDY'S LABORATORIES LTD. (IN) 2008-08-21 WO claimed
CN-120346211-B Application of diphenyl acetonitrile compounds and protein-targeted hydrolysis chimeric compounds 中国科学技术大学 2025-10-24 CN disclosed
US-4120969-A ANALGETIC, ANTIDIARRHEAL ACTIVITY A. H. ROBINS COMPANY, INCORPORATED (US) 1978-10-17 US disclosed