Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542905 | 0.88 | ALDH1A1 (0.32) | KMT2AMEN1ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL10545169 | 0.87 | MEN1 (0.31) | KMT2AMEN1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL10540518 | 0.87 | MEN1 (0.31) | KMT2AMEN1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL11473393 | 0.85 | KMT2A (0.33) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL11540074 | 0.83 | MAPT (0.36) | SMN1; SMN2MAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL10544967 | 0.83 | KDM4E (0.32) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL10890403 | 0.81 | BRD4 (0.36) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10884861 | 0.79 | ALDH1A1 (0.35) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8015627 | 0.78 | PIP5K1C (0.41) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8019417 | 0.78 | KDM4E (0.38) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174318-A | USING A TRIALKYL- OR TRIALKYLAMINOPHOSPHINE AS REDUCING AGENT | GLAXO LABORATORIES LTD. (GB) | 1979-11-13 | — | — | US | disclosed |