Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537076 | 0.89 | DRD4 (0.53) | DRD4DRD2KDM4EADRB2ADRB1 | |
| SCHEMBL11538737 | 0.85 | MEN1 (0.56) | MEN1KMT2AHTTUSP2ATM | |
| SCHEMBL11538455 | 0.79 | TP53 (0.37) | MEN1KMT2AHTTUSP2DRD4 | |
| Hydrochloric Acid SCHEMBL11542328 | 0.79 | KMT2A (0.61) | MEN1KMT2AHTTUSP2ATM | |
| SCHEMBL11538412 | 0.76 | KMT2A (0.51) | MEN1KMT2AATMDRD4DRD2 | |
| Hydrochloric Acid SCHEMBL11538853 | 0.76 | KMT2A (0.52) | MEN1KMT2AATMDRD4DRD2 | |
| SCHEMBL11499199 | 0.74 | DRD4 (0.53) | DRD4DRD2KDM4EADRB2ADRB1 | |
| SCHEMBL11377069 | 0.73 | ADRB3 (0.53) | MEN1KMT2ADRD4DRD2ADRB2 | |
| SCHEMBL11541253 | 0.73 | DRD4 (0.38) | DRD4MAPTABCB1DCPS | |
| Hydrochloric Acid SCHEMBL11541088 | 0.72 | P2RY1 (0.38) | DRD4MAPTABCB1DCPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146630-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-27 | — | — | US | disclosed |