Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DCPS | Q96C86 | 4/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538452 | 0.89 | TP53 (0.37) | TP53ALPLALPIALPGSMN1; SMN2 | |
| SCHEMBL11538745 | 0.79 | MEN1 (0.56) | SMN1; SMN2DCPSMETAP2MEN1KMT2A | |
| SCHEMBL11541253 | 0.75 | DRD4 (0.38) | DCPSDRD4 | |
| Hydrochloric Acid SCHEMBL11541088 | 0.75 | P2RY1 (0.38) | DCPSDRD4 | |
| SCHEMBL11537076 | 0.69 | DRD4 (0.53) | TSHRDRD4 | |
| Hydrochloric Acid SCHEMBL11370276 | 0.68 | KMT2A (0.36) | MEN1KMT2ADRD4PDE4BPDE4A | |
| SCHEMBL11544386 | 0.66 | HTR1A (0.47) | — | |
| SCHEMBL11538737 | 0.66 | MEN1 (0.56) | MEN1KMT2ADRD4USP2HTT | |
| Hydrochloric Acid SCHEMBL11370273 | 0.66 | KMT2A (0.36) | MEN1KMT2ADRD4PDE4BPDE4A | |
| SCHEMBL10572054 | 0.66 | SCN1A (0.49) | TP53SMN1; SMN2TSHRDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146630-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-27 | — | — | US | disclosed |