Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3154691 | 0.82 | ALDH1A1 (0.41) | — | |
| SCHEMBL203099 | 0.80 | LMNA (0.39) | KDM4E | |
| SCHEMBL17818836 | 0.79 | SMN1; SMN2 (0.36) | SMN1; SMN2KDM4E | |
| SCHEMBL3474604 | 0.78 | TSHR (0.37) | — | |
| SCHEMBL19759001 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL20708377 | 0.75 | LMNA (0.39) | SMN1; SMN2KDM4E | |
| SCHEMBL7847493 | 0.75 | TSHR (0.46) | SMN1; SMN2KDM4E | |
| SCHEMBL11076777 | 0.74 | ALDH1A1 (0.38) | — | |
| SCHEMBL24465045 | 0.74 | — | — | |
| SCHEMBL11245204 | 0.72 | LMNA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167632-A | APPETITE SUPPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1979-09-11 | — | — | US | disclosed |
| US-4122265-A | APPETITE SUPPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1978-10-24 | — | — | US | disclosed |