Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13033282 | 0.90 | MEN1 (0.54) | MEN1KMT2ASIGMAR1HSD17B10CASP2 | |
| SCHEMBL30645317 | 0.88 | GNAI3 (0.52) | CASP2GNAI3GNAO1GNAI1KDM4E | |
| SCHEMBL11981498 | 0.81 | SMN1; SMN2 (0.50) | MEN1KMT2ASIGMAR1HSD17B10CASP2 | |
| SCHEMBL18784666 | 0.79 | GNAI3 (0.58) | MEN1KMT2ASIGMAR1HSD17B10CASP2 | |
| SCHEMBL18784665 | 0.79 | GNAI3 (0.58) | MEN1KMT2ASIGMAR1HSD17B10CASP2 | |
| SCHEMBL84809 | 0.78 | ALDH1A1 (0.55) | MEN1KMT2ACASP2KDM4EGAA | |
| SCHEMBL12933657 | 0.78 | KMT2A (0.47) | MEN1KMT2ASIGMAR1HSD17B10CHRM5 | |
| SCHEMBL8572773 | 0.77 | MEN1 (0.56) | MEN1KMT2ASIGMAR1HSD17B10CHRM5 | |
| SCHEMBL84807 | 0.77 | ALDH1A1 (0.58) | MEN1KMT2ACASP2KDM4EALDH1A1 | |
| SCHEMBL8408995 | 0.77 | HDAC2 (0.49) | CASP2KDM4EALDH1A1CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137416-A | 2-Acylamidoethyl-2-imidazolines | AMERICAN CYANAMID COMPANY (US) | 1979-01-30 | — | — | US | disclosed |