Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | FABP2 | P12104 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4398676 | 0.90 | PPARA (0.51) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11539611 | 0.85 | SLC22A12 (0.48) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11541549 | 0.81 | CYP1A2 (0.57) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4192083 | 0.81 | PPARA (0.59) | PPARAKMT2APPARGTBXAS1 | |
| SCHEMBL7302773 | 0.80 | ALDH1A1 (0.45) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14309703 | 0.80 | SLC22A12 (0.54) | PPARACYP1A2MAPTSLC22A12PPARG | |
| SCHEMBL13945735 | 0.79 | MAOA (0.47) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7298915 | 0.77 | ALDH1A1 (0.49) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11540004 | 0.75 | MAOA (0.40) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9320807 | 0.75 | PPARA (0.89) | PPARAMEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156011-A | TREATMENT OF CARDIOVASCULAR DISORDERS | SOCIETE ANONYME DITE: LABORATOIRE L. LAFON (FR) | 1979-05-22 | — | — | US | disclosed |