Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538507 | 0.83 | CYP19A1 (0.55) | ALDH1A1CYP19A1MEN1KMT2ACYP3A4 | |
| SCHEMBL11538609 | 0.82 | SLC6A2 (0.50) | RAB9AGAACYP19A1KDM4ECYP3A4 | |
| SCHEMBL10197954 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9AALDH1A1GAAKDM4E | |
| SCHEMBL11540443 | 0.80 | KCNQ3 (0.44) | CYP19A1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL11541310 | 0.77 | CYP19A1 (0.58) | RAB9ACYP19A1KDM4ECYP3A4CYP2D6 | |
| SCHEMBL82409 | 0.75 | — | — | |
| SCHEMBL31032336 | 0.75 | — | — | |
| SCHEMBL122911 | 0.75 | ACHE (0.57) | ALDH1A1GAACYP19A1MEN1KMT2A | |
| SCHEMBL11537552 | 0.74 | CYP19A1 (0.34) | ALDH1A1GAACYP19A1MEN1KMT2A | |
| SCHEMBL1090665 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9ACYP3A4CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138488-A | Diphenylmethyl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |