Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10438572 | 0.81 | TSHR (0.53) | ADRB2TSHRMAPTTDP1ALDH1A1 | |
| SCHEMBL9290109 | 0.80 | ADRB2 (0.54) | ADRB2TSHRMAPTTDP1ALDH1A1 | |
| SCHEMBL28990038 | 0.78 | ADRB2 (0.49) | ADRB2TSHRMAPTTDP1ALDH1A1 | |
| SCHEMBL10800795 | 0.78 | ADRB2 (0.49) | ADRB2TSHRMAPTTDP1ALDH1A1 | |
| SCHEMBL978898 | 0.77 | TSHR (0.59) | ADRB2TSHRMAPTTDP1ALDH1A1 | |
| SCHEMBL7604891 | 0.74 | TSHR (0.56) | ADRB2TSHRMAPTTDP1ALDH1A1 | |
| SCHEMBL20362349 | 0.74 | TSHR (0.56) | ADRB2TSHRMAPTTDP1ALDH1A1 | |
| SCHEMBL11572879 | 0.73 | MAPT (0.49) | ADRB2TSHRMAPTTDP1ALDH1A1 | |
| SCHEMBL16654104 | 0.72 | TSHR (0.53) | ADRB2TSHRMAPTTDP1ALDH1A1 | |
| SCHEMBL10607024 | 0.72 | ADRB2 (0.59) | ADRB2TSHRMAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154846-A | ANTHELMINTICS | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |