Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.39 |
| ▸ | TLR2 | O60603 | 3/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7369678 | 0.99 | CTSK (0.45) | CTSKCTSSSIRT1SIRT6ITGB3 | |
| Hydrochloric Acid SCHEMBL7376884 | 0.99 | CTSK (0.45) | CTSKCTSSSIRT1SIRT6ITGB3 | |
| SCHEMBL19692119 | 0.92 | CTSK (0.45) | CTSKCTSS | |
| SCHEMBL28190852 | 0.90 | CTSK (0.55) | CTSKCTSS | |
| SCHEMBL30466182 | 0.90 | CTSK (0.52) | CTSKCTSSITGB3ITGA2B | |
| SCHEMBL29931123 | 0.87 | ITGB3 (0.39) | CTSKCTSSITGB3ITGA2BATM | |
| SCHEMBL8823889 | 0.86 | ERAP2 (0.46) | SIRT1SIRT6TLR2SIRT2SIRT3 | |
| SCHEMBL10766995 | 0.86 | ERAP2 (0.46) | SIRT1SIRT6TLR2SIRT2SIRT3 | |
| SCHEMBL11783967 | 0.86 | ERAP2 (0.46) | SIRT1SIRT6TLR2SIRT2SIRT3 | |
| SCHEMBL7150850 | 0.86 | CTSK (0.49) | CTSKCTSSITGB3ITGA2BATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133839-A1 | METHODS OF PREPARING N6-((2-AZIDOETHOXY)CARBONYL)LYSINE | Synthorx, Inc. (US) | 2021-07-01 | — | — | WO | disclosed |
| EP-3024823-A2 | INTERCALATING AMINO ACIDS | Universität Konstanz (DE) | 2016-06-01 | — | — | EP | disclosed |
| WO-2015011081-A2 | INTERCALATING AMINO ACIDS | UNIVERSITAET KONSTANZ (DE) | 2015-01-29 | — | — | WO | disclosed |
| US-4178291-A | HYPOTENSIVE AGENTS, ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-12-11 | — | — | US | disclosed |
| US-4176235-A | ANGIOTENSIN COVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-11-27 | — | — | US | disclosed |
| US-4175199-A | Substituted acyl derivatives of amino acids | E. R. SQUIBB & SONS, INC. (US) | 1979-11-20 | — | — | US | disclosed |
| US-4140864-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4116962-A | ANGIOTENSIN CONVERTING ENXYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-26 | — | — | US | disclosed |