Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 3/20 | 0.50 |
| ▸ | ARG2 | P78540 | 2/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ODC1 | P11926 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SPTLC1 | O15269 | 1/20 | 0.35 |
| ▸ | SPTLC2 | O15270 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | GGT1 | P19440 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515330 | 1.00 | ARG1 (0.50) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL8768541 | 0.83 | ARG1 (0.40) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL22009572 | 0.83 | ARG1 (0.40) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL22009377 | 0.83 | ARG1 (0.40) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL2129918 | 0.80 | ARG1 (0.50) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL29777967 | 0.80 | ARG1 (0.50) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL16116350 | 0.80 | ARG1 (0.50) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL3110575 | 0.79 | ARG1 (0.38) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL3110569 | 0.79 | ARG1 (0.38) | ARG1ARG2NOS3NOS1NOS2 | |
| SCHEMBL16222763 | 0.78 | ARG1 (0.48) | ARG1ARG2NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145549-A | CYCLIZATION, SOLVOLYSIS | SANDOZ LTD. (CH) | 1979-03-20 | — | — | US | disclosed |