SCHEMBL8768541

SCHEMBL8768541

CC(N)C(N)(CO)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 2/20 0.40
ARG2 P78540 1/20 0.40
ODC1 P11926 1/20 0.36
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
GABRP O00591 2/20 0.34
GABRD O14764 2/20 0.34
GABRA1 P14867 2/20 0.34
GABRB1 P18505 2/20 0.34
GABRG2 P18507 2/20 0.34
GABRB3 P28472 2/20 0.34
GABRA5 P31644 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1515330 0.83 ARG1 (0.50) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL11539532 0.83 ARG1 (0.50) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL22009377 0.81 ARG1 (0.40) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL22009572 0.81 ARG1 (0.40) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL5319944 0.81 ARG1 (0.40) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL2156784 0.77 ODC1 (0.47) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL3110575 0.77 ARG1 (0.38) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL3110569 0.77 ARG1 (0.38) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL638315 0.76 ARG1 (0.37) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL21802412 0.74 ODC1 (0.63) ARG1ARG2ODC1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0792146-A1 INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES HEMASURE, INC. (US) 1997-09-03 EP disclosed
WO-1997002028-A1 INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES HEMASURE, INC. (US) 1997-01-23 WO disclosed