Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11534743 | 0.93 | CYP19A1 (0.44) | CYP19A1PGRLMNACYP2C9MAPK14 | |
| SCHEMBL11534023 | 0.91 | CYP19A1 (0.46) | CYP19A1LMNANPC1POLBRAB9A | |
| SCHEMBL11570831 | 0.90 | CYP19A1 (0.42) | CYP19A1BCL2L1MCL1PGRLMNA | |
| SCHEMBL11534596 | 0.88 | CYP19A1 (0.55) | CYP19A1BCL2L1MCL1S1PR1LMNA | |
| SCHEMBL11534523 | 0.87 | CYP19A1 (0.46) | CYP19A1LMNACYP2C9POLBCYP3A4 | |
| SCHEMBL11534709 | 0.86 | TSHR (0.47) | CYP19A1LMNACYP2C9CYP2D6PPARG | |
| SCHEMBL11533030 | 0.86 | KMT2A (0.47) | CYP19A1LMNARAB9ACYP3A4MEN1 | |
| SCHEMBL11537539 | 0.85 | TSHR (0.46) | CYP19A1LMNACYP2C9PPARGMAPK14 | |
| SCHEMBL11536254 | 0.83 | MAPT (0.45) | CYP19A1LMNAMAPK14NPC1RAB9A | |
| SCHEMBL11531951 | 0.83 | KMT2A (0.46) | CYP19A1LMNARAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |