Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | FABP1 | P07148 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11534743 | 0.94 | CYP19A1 (0.44) | CYP19A1TDP1MAPTALDH1A1MGLL | |
| SCHEMBL11530465 | 0.90 | ALDH1A1 (0.42) | CYP19A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL11539604 | 0.90 | CYP19A1 (0.53) | CYP19A1MEN1KMT2AMCL1BCL2L1 | |
| SCHEMBL11534709 | 0.87 | TSHR (0.47) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11533550 | 0.87 | TSHR (0.44) | CYP19A1MEN1KMT2ATDP1MCL1 | |
| SCHEMBL11537539 | 0.86 | TSHR (0.46) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11536254 | 0.84 | MAPT (0.45) | CYP19A1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL11534227 | 0.84 | LMNA (0.47) | CYP19A1TDP1MAPTALDH1A1LMNA | |
| SCHEMBL11533723 | 0.83 | SMN1; SMN2 (0.44) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL11538658 | 0.83 | CYP19A1 (0.45) | CYP19A1MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |