Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.95 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.95 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | F13A1 | P00488 | 1/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL274906 | 0.98 | TMEM97 (1.00) | TMEM97SIGMAR1TAAR1MAPTHIF1A | |
| Hydrochloric Acid SCHEMBL5115776 | 0.95 | TMEM97 (0.95) | TMEM97SIGMAR1TAAR1MAPTHIF1A | |
| Bromide SCHEMBL6337077 | 0.95 | TMEM97 (0.95) | TMEM97SIGMAR1TAAR1MAPTHIF1A | |
| Hydrochloric Acid SCHEMBL28659483 | 0.93 | TMEM97 (0.91) | TMEM97SIGMAR1TAAR1MAPTHIF1A | |
| Hydrochloric Acid SCHEMBL27960798 | 0.93 | TMEM97 (0.91) | TMEM97SIGMAR1TAAR1MAPTHIF1A | |
| Nitrous Acid SCHEMBL18329343 | 0.88 | TMEM97 (0.81) | TMEM97SIGMAR1TAAR1MAPTHIF1A | |
| Tyramine SCHEMBL27589422 | 0.88 | TMEM97 (0.81) | TMEM97SIGMAR1TAAR1MAPTHIF1A | |
| SCHEMBL579569 | 0.86 | TMEM97 (0.78) | TMEM97SIGMAR1TAAR1MAPTHIF1A | |
| SCHEMBL10156581 | 0.85 | TAAR1 (0.76) | TMEM97SIGMAR1TAAR1MAPTHIF1A | |
| Nitric Acid SCHEMBL18329335 | 0.85 | TMEM97 (0.75) | TMEM97SIGMAR1TAAR1MAPTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156010-A | TREATMENT OF GLAUCOMA | MERCK & CO., INC. (US) | 1979-05-22 | — | — | US | disclosed |