SCHEMBL274906

SCHEMBL274906

CNCCc1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TMEM97 Q5BJF2 2/20 1.00
SIGMAR1 Q99720 2/20 1.00
TAAR1 Q96RJ0 5/20 0.61
MAPT P10636 2/20 0.61
HIF1A Q16665 2/20 0.61
TP53 P04637 1/20 0.61
CYP1A2 P05177 1/20 0.61
ALOX15 P16050 1/20 0.61
TSHR P16473 1/20 0.61
NFKB1 P19838 1/20 0.61
MAPK1 P28482 1/20 0.61
THPO P40225 1/20 0.61
HSD17B10 Q99714 1/20 0.61
ATM Q13315 1/20 0.60
ESR1 P03372 2/20 0.59
ESR2 Q92731 2/20 0.59
KDM4E B2RXH2 3/20 0.59
LMNA P02545 3/20 0.59
ALDH1A1 P00352 2/20 0.59
F13A1 P00488 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL6337077 0.98 TMEM97 (0.95) TMEM97SIGMAR1TAAR1MAPTHIF1A
Hydrochloric Acid SCHEMBL5115776 0.98 TMEM97 (0.95) TMEM97SIGMAR1TAAR1MAPTHIF1A
SCHEMBL11539730 0.98 TMEM97 (0.95) TMEM97SIGMAR1TAAR1MAPTHIF1A
Hydrochloric Acid SCHEMBL28659483 0.96 TMEM97 (0.91) TMEM97SIGMAR1TAAR1MAPTHIF1A
Hydrochloric Acid SCHEMBL27960798 0.96 TMEM97 (0.91) TMEM97SIGMAR1TAAR1MAPTHIF1A
Nitrous Acid SCHEMBL18329343 0.90 TMEM97 (0.81) TMEM97SIGMAR1TAAR1MAPTHIF1A
Tyramine SCHEMBL27589422 0.90 TMEM97 (0.81) TMEM97SIGMAR1TAAR1MAPTHIF1A
SCHEMBL579569 0.88 TMEM97 (0.78) TMEM97SIGMAR1TAAR1MAPTHIF1A
SCHEMBL10156581 0.87 TAAR1 (0.76) TMEM97SIGMAR1TAAR1MAPTHIF1A
Nitric Acid SCHEMBL18329335 0.87 TMEM97 (0.75) TMEM97SIGMAR1TAAR1MAPTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 905 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122056926-A Probiotic composition containing melatonin and application of composition in sleep 南京北极光生物科技有限公司 2026-05-19 CN claimed
US-20260130363-A1 PEST ANT BAIT COMPOSITIONS AND METHODS THE US SECRETARY OF AGRICULTURE (US) 2026-05-14 US claimed
EP-4514146-B1 A COMBINATION FOR USE IN THE PREPARATION OF A DRINKABLE FOAMING OR FOAMABLE LIQUID, A DEVICE AND A METHOD FOR PREPARING AND DISPENSING A DRINKABLE FOAMING OR FOAMABLE LIQUID BAR ON B V (BE) 2026-05-13 EP claimed
US-12533327-B2 Hexylamine salts and methods of using hexylamine THERMOLIFE INTERNATIONAL, LLC (US) 2026-01-27 US claimed
EP-4514146-A1 A COMBINATION FOR USE IN THE PREPARATION OF A DRINKABLE FOAMING OR FOAMABLE LIQUID, A DEVICE AND A METHOD FOR PREPARING AND DISPENSING A DRINKABLE FOAMING OR FOAMABLE LIQUID Bar.on B.V. (BE) 2025-03-05 EP claimed
CN-119165087-A Method for detecting multiple components in rhizoma coptidis green particles 上海市第七人民医院(上海中医药大学附属第七人民医院) 2024-12-20 CN claimed
US-20240358735-A1 THERAPEUTIC COMPOSITIONS AND RELATED METHODS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-10-31 US claimed
CN-118688315-A Multichannel high-coverage synchronous quantification method for amino-containing and hydroxyl-containing compounds 复旦大学 2024-09-24 CN claimed
EP-4392037-A1 THERAPEUTIC COMPOSITIONS AND RELATED METHODS Boyce Thompson Institute for Plant Research Inc. (US) 2024-07-03 EP claimed
CN-117789993-B Establishment and application of gastric cancer prediction model based on tongue fur metabolite 浙江省肿瘤医院 2024-06-11 CN claimed
US-6447818-B1 SYNERGISTIC DIETETICS COMPRISING PLANT EXTRACTS CONTAINING FLAVANOIDS AND GLUCOSIDES, AND EPHEDRINE, SYNEPHRINE, PSEUDOEPHEDRINE, TYRAMINES, OCTOPAMINE AND HORDENINE; HYPOTENSIVE AGENTS AMBROS PHARMA S.R.L. (IT) 2002-09-10 US claimed
US-20020058075-A1 Methods for inducing weight loss in a human with materials derived from citrus varieties ZHISHIN, LLC 2002-05-16 US claimed
US-6340482-B1 ADMINISTERING BY MOUTH ADRENERGIC AMINE OR AMINES SELECTED FROM THE GROUP CONSISTING OF SYNEPHRINE, HORDENINE, OCTOPAMINE, TYRAMINE AND N-METHYLTYRAMINE FOR SUPPRESSING HUNGER FOR INDUCING WEIGHT LOSS ZHISHIN, LLC 2002-01-22 US claimed
US-6340481-B1 ADMINISTERING BY MOUTH TO A HUMAN FORMULATION COMPRISING ADRENERGIC AMINE OR AMINES SELECTED FROM THE GROUP CONSISTING OF SYNEPHRINE, HORDENINE, OCTOPAMINE, TYRAMINE AND N-METHYLTYRAMINEENHANCING PHYSICAL PERFORMANCE IN A HUMAN ZHISHIN, LLC 2002-01-22 US claimed
US-6316499-B1 ADMINISTERING FORMULATION COMPRISING ASUBSTANCE OR SUBSTANCES SELECTED FROM SYNEPHRINE, HORDENINE, SYNEPHRINE, HORDENINE, OCTOPAMINE, TYRAMINE AND N-METHYLTYRAMINE FOR INCREASING MUSCLE MASS OF HUMAN ZHISHIN, LLC 2001-11-13 US claimed
US-6224873-B1 STIMULATING THERMOGENESIS IN HUMANS ZHISHIN, LLC 2001-05-01 US claimed
EP-1093817-A1 Composition containing compounds with adrenergic activity and vegetable extracts of crataegus and gingko biloba for the treatment of overweight and obesity Ambros Pharma S.r.l. (IT) 2001-04-25 EP claimed
EP-0885008-A4 THE REGULATION OF APPETITE, BODY WEIGHT AND ATHLETIC FUNCTION WITH MATERIALS DERIVED FROM CITRUS VARIETIES JONES DENNIS (US) 2000-12-20 EP claimed
EP-0885008-A1 THE REGULATION OF APPETITE, BODY WEIGHT AND ATHLETIC FUNCTION WITH MATERIALS DERIVED FROM CITRUS VARIETIES Jones, Dennis (US) 1998-12-23 EP claimed
WO-1998014200-A1 THE REGULATION OF APPETITE, BODY WEIGHT AND ATHLETIC FUNCTION WITH MATERIALS DERIVED FROM CITRUS VARIETIES JONES DENNIS (US) 1998-04-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533327-B2 Hexylamine salts and methods of using hexylamine SLC6A2, SLC6A3, COMT TMEM97 1294/4885SIGMAR1 358/4885TAAR1 8/4885
US-20240358735-A1 THERAPEUTIC COMPOSITIONS AND RELATED METHODS MAG, PMP22, B3GAT3 TMEM97 4457/4885SIGMAR1 4156/4885TAAR1 4682/4885
US-20260130363-A1 PEST ANT BAIT COMPOSITIONS AND METHODS AMY1A, STOM, PTMS TMEM97 385/4885SIGMAR1 1365/4885TAAR1 160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.