Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539746 | 1.00 | TSHR (0.48) | TSHRMAPK10CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL11543609 | 0.86 | PLA2G1B (0.50) | TSHRMAPK10ALDH1A1MAPTMEN1 | |
| SCHEMBL11543614 | 0.86 | PLA2G1B (0.50) | TSHRMAPK10ALDH1A1MAPTMEN1 | |
| SCHEMBL5238435 | 0.85 | ALDH1A1 (0.54) | TSHRMAPK10ALDH1A1ALOX12HPGD | |
| SCHEMBL5238423 | 0.85 | ALDH1A1 (0.54) | TSHRMAPK10ALDH1A1ALOX12HPGD | |
| SCHEMBL5238428 | 0.85 | ALDH1A1 (0.54) | TSHRMAPK10ALDH1A1ALOX12HPGD | |
| SCHEMBL10396872 | 0.81 | MEN1 (0.51) | TSHRMAPK10CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL10396875 | 0.81 | MEN1 (0.51) | TSHRMAPK10CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL11410241 | 0.76 | TSHR (0.47) | TSHRMAPK10ALDH1A1MAPK1 | |
| SCHEMBL11410237 | 0.76 | TSHR (0.47) | TSHRMAPK10ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154599-A | Alkylthioaminoacrylonitriles and use as herbicides | GULF OIL CORPORATION (US) | 1979-05-15 | — | — | US | claimed |