Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5238435 | 1.00 | ALDH1A1 (0.54) | ALDH1A1HPGDALOX12TSHRMAPK10 | |
| SCHEMBL5238423 | 1.00 | ALDH1A1 (0.54) | ALDH1A1HPGDALOX12TSHRMAPK10 | |
| SCHEMBL11539746 | 0.85 | TSHR (0.48) | ALDH1A1HPGDALOX12TSHRMAPK10 | |
| SCHEMBL11543614 | 0.85 | PLA2G1B (0.50) | ALDH1A1TSHRMAPK10GAAMEN1 | |
| SCHEMBL11543609 | 0.85 | PLA2G1B (0.50) | ALDH1A1TSHRMAPK10GAAMEN1 | |
| SCHEMBL11539748 | 0.85 | TSHR (0.48) | ALDH1A1HPGDALOX12TSHRMAPK10 | |
| SCHEMBL5234638 | 0.85 | NPC1 (0.50) | ALDH1A1HPGDALOX12GAAMEN1 | |
| SCHEMBL11410237 | 0.84 | TSHR (0.47) | ALDH1A1TSHRMAPK10 | |
| SCHEMBL11410241 | 0.84 | TSHR (0.47) | ALDH1A1TSHRMAPK10 | |
| SCHEMBL5235665 | 0.83 | KMT2A (0.47) | ALDH1A1HPGDGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | SANKYO COMPANY, LIMITED (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | RASGRP1, NRAS, HRH3 | ALDH1A1 1073/4885HPGD 2215/4885ALOX12 4701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.