Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539745 | 1.00 | MEN1 (0.52) | MEN1ALDH1A1KMT2APTGS2CHRM5 | |
| SCHEMBL11541863 | 0.82 | ALDH1A1 (0.48) | MEN1ALDH1A1KMT2APTGS2CHRM5 | |
| SCHEMBL11541865 | 0.82 | ALDH1A1 (0.48) | MEN1ALDH1A1KMT2APTGS2CHRM5 | |
| SCHEMBL22791460 | 0.80 | TAAR1 (0.57) | MEN1ALDH1A1KMT2ACHRM5TAAR1 | |
| SCHEMBL14198012 | 0.79 | CHRM5 (0.58) | MEN1ALDH1A1KMT2ACHRM5TAAR1 | |
| SCHEMBL5418658 | 0.77 | AKR1C3 (0.50) | ALDH1A1PTGS2 | |
| SCHEMBL4619195 | 0.77 | AKR1C3 (0.50) | ALDH1A1PTGS2 | |
| SCHEMBL5419434 | 0.77 | AKR1C3 (0.50) | ALDH1A1PTGS2 | |
| SCHEMBL11538352 | 0.77 | AKR1C3 (0.49) | MEN1ALDH1A1KMT2ACHRM5MAPT | |
| SCHEMBL11538355 | 0.77 | AKR1C3 (0.49) | MEN1ALDH1A1KMT2ACHRM5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136180-A | HYPOLIPIDEMIC SUBSTITUTED STYRENESULFONYLUREAS | PFIZER INC. (US) | 1979-01-23 | — | — | US | disclosed |
| US-4062960-A | Hypolipidemic alkenesulfonamides | PFIZER INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3983107-A | ARTERIOSCLEROSIS | PFIZER INC. (US) | 1976-09-28 | — | — | US | disclosed |