SCHEMBL11539848

SCHEMBL11539848

CCN(NS(C)(=O)=O)c1ccc(C)c(O)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
CYP1A2 P05177 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
MEN1 O00255 1/20 0.36
CYP3A4 P08684 1/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
ESR1 P03372 3/20 0.36
RAB9A P51151 4/20 0.35
MAPT P10636 4/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
NPC1 O15118 2/20 0.34
NR3C2 P08235 1/20 0.34
TSHR P16473 1/20 0.33
CASP1 P29466 1/20 0.33
HSD17B2 P37059 1/20 0.33
LMNA P02545 2/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9737708 0.79 S100B (0.54) ALDH1A1CYP3A4GAAESR1RAB9A
Sulfuric Acid SCHEMBL10429918 0.78 S100B (0.50) ALDH1A1CYP2C9CYP2C19MEN1CYP3A4
SCHEMBL11448714 0.75 POLB (0.45) ALDH1A1GAAKMT2AMAPTSMN1; SMN2
SCHEMBL8682651 0.74 TAAR1 (0.36) NR3C2
Hydrochloric Acid SCHEMBL11418494 0.74 POLB (0.44) ALDH1A1GAAKMT2AMAPTSMN1; SMN2
SCHEMBL9494176 0.73 S100B (0.36) ALDH1A1CYP3A4RAB9AMAPTNR3C2
Sulfuric Acid SCHEMBL10826964 0.72 ALDH1A1 (0.43) ALDH1A1CYP2D6CYP2C9CYP2C19MEN1
SCHEMBL9512119 0.72 NR3C2 (0.51) ALDH1A1MEN1KMT2AESR1MAPT
Sulfuric Acid SCHEMBL8070181 0.71 NR3C2 (0.47) ALDH1A1MEN1KMT2AESR1NR3C2
SCHEMBL1599726 0.71 S100B (0.55) ALDH1A1MEN1CYP3A4GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4149848-A N-/TETRAHYDROFURFURYL/P-PHENYLENEDIAMINES L'OREAL (FR) 1979-04-17 US disclosed