Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539450 | 0.87 | ADRB2 (0.47) | DRD4ADRB2ADRB1ADRB3 | |
| SCHEMBL11539298 | 0.86 | P2RY1 (0.39) | DRD4DRD2P2RY1ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11544679 | 0.85 | P2RY1 (0.39) | DRD4DRD2P2RY1ADRB2ADRB1 | |
| SCHEMBL11541245 | 0.85 | HTR3A (0.40) | DRD4P2RY1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL11541081 | 0.84 | HTR3A (0.39) | DRD4P2RY1ADRB2ADRB1ADRB3 | |
| SCHEMBL11537535 | 0.83 | DRD4 (0.56) | DRD4DRD2ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL11372638 | 0.82 | ADRB2 (0.43) | DRD4P2RY1ADRB2ADRB1ADRB3 | |
| SCHEMBL11541253 | 0.82 | DRD4 (0.38) | DRD4P2RY1CARM1PRMT6ABCB1 | |
| Hydrochloric Acid SCHEMBL11541088 | 0.81 | P2RY1 (0.38) | DRD4P2RY1CARM1PRMT6ABCB1 | |
| SCHEMBL6295417 | 0.78 | ADRB2 (0.49) | DRD4ADRB2ADRB1ADRB3ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146630-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-27 | — | — | US | disclosed |