Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AQP1 | P29972 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538214 | 0.86 | KDM4E (0.58) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL11539001 | 0.85 | KDM4E (0.57) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL11540082 | 0.84 | KDM4E (0.56) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL11540442 | 0.83 | KDM4E (0.56) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL11543007 | 0.81 | KDM4E (0.51) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL11540030 | 0.81 | KDM4E (0.55) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL11543688 | 0.80 | CA2 (0.38) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL11538413 | 0.79 | KDM4E (0.53) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL7291013 | 0.79 | KDM4E (0.53) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL11543530 | 0.79 | CA2 (0.58) | KDM4EUSP2ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176190-A | Diuretic and saliuretic sulphamoylbenzoic acids | CIBA-GEIGY CORPORATION (US) | 1979-11-27 | — | — | US | disclosed |