Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.50 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3780641 | 0.86 | S100A4 (0.56) | S100A4PRKCIMAPTALDH1A1NPC1 | |
| SCHEMBL11725835 | 0.86 | S100A4 (0.56) | S100A4MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL11542046 | 0.84 | MAOB (0.48) | S100A4PRKCIMAPTALDH1A1NPC1 | |
| SCHEMBL11540945 | 0.83 | S100A4 (0.53) | S100A4MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL11308153 | 0.83 | S100A4 (0.56) | S100A4MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL11739637 | 0.81 | PRKCI (0.44) | S100A4PRKCIMAPTNPC1RAB9A | |
| SCHEMBL11541429 | 0.78 | L3MBTL1 (0.49) | S100A4MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3800105 | 0.78 | MAPT (0.55) | S100A4PRKCIMAPTALDH1A1NPC1 | |
| SCHEMBL935912 | 0.77 | PRKCI (0.56) | PRKCIMAPTALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9537225 | 0.77 | MAPT (0.53) | S100A4PRKCIMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153807-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS | THE BOOTS COMPANY LIMITED (GB) | 1979-05-08 | — | — | US | disclosed |
| US-4048332-A | Phenylalkanoic acids | THE BOOTS COMPANY LIMITED (EN) | 1977-09-13 | — | — | US | disclosed |