Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532100 | 0.94 | CYP19A1 (0.62) | CYP19A1LMNATYRKIF11ALDH1A1 | |
| SCHEMBL11532548 | 0.92 | CYP19A1 (0.85) | CYP19A1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11531968 | 0.82 | CYP19A1 (1.00) | CYP19A1KMT2ATSHR | |
| SCHEMBL11535106 | 0.82 | CYP19A1 (0.70) | CYP19A1RAB9AUSP2 | |
| SCHEMBL11533235 | 0.82 | CYP19A1 (0.70) | CYP19A1TRPV1ADRA1ARAB9AADRA2A | |
| Hydrochloric Acid SCHEMBL11532663 | 0.81 | CYP19A1 (0.68) | CYP19A1KIF11NISCHRAB9AMAPT | |
| SCHEMBL660544 | 0.78 | CYP19A1 (0.62) | CYP19A1ALDH1A1KDM4ENISCHSMN1; SMN2 | |
| SCHEMBL6090949 | 0.78 | CYP19A1 (0.64) | CYP19A1KMT2ATSHRADRA1ANISCH | |
| SCHEMBL11535538 | 0.78 | CYP19A1 (0.51) | CYP19A1ALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL11533232 | 0.77 | CYP19A1 (0.62) | CYP19A1KIF11ALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152441-A | Analgesic imidazolemethanols | GIST-BROCADES N.V. (NL) | 1979-05-01 | — | — | US | disclosed |