Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 3/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538228 | 0.83 | EPHX2 (0.51) | IDO1HPGDMAPTALOX15MEN1 | |
| SCHEMBL6764765 | 0.79 | SMN1; SMN2 (0.45) | IDO1HPGDMAPTALOX15MEN1 | |
| SCHEMBL30046067 | 0.72 | TRPA1 (0.65) | IDO1TDP1TP53HPGDMAPT | |
| SCHEMBL278520 | 0.72 | TRPA1 (0.65) | IDO1TDP1TP53HPGDMAPT | |
| SCHEMBL29763149 | 0.72 | TRPA1 (0.65) | IDO1TDP1TP53HPGDMAPT | |
| SCHEMBL1628070 | 0.70 | EPHX2 (0.65) | IDO1TDP1TP53HPGDMAPT | |
| SCHEMBL18171927 | 0.69 | TDP1 (0.58) | IDO1TDP1TP53HPGDMAPT | |
| SCHEMBL21097057 | 0.68 | NPC1 (0.45) | IDO1TDP1HPGDMAPTMEN1 | |
| SCHEMBL12714307 | 0.67 | TRPA1 (0.52) | IDO1TDP1TP53HPGDMAPT | |
| SCHEMBL23590408 | 0.67 | CYP19A1 (0.54) | TP53MAPTMEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153707-A | Fungicidal isoxazolyl phenols and method of use | THE UPJOHN COMPANY (US) | 1979-05-08 | — | — | US | claimed |
| US-4153707-A | Fungicidal isoxazolyl phenols and method of use | THE UPJOHN COMPANY (US) | 1979-05-08 | — | — | US | disclosed |