SCHEMBL278520

SCHEMBL278520

Cc1ccc(O)c(-c2cc(C)ccc2O)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.65
TDP1 Q9NUW8 3/20 0.62
TP53 P04637 2/20 0.62
ALOX15 P16050 5/20 0.56
HSD17B10 Q99714 4/20 0.56
ALDH1A1 P00352 3/20 0.56
IDO1 P14902 1/20 0.55
HPGD P15428 6/20 0.54
MAPT P10636 5/20 0.54
LMNA P02545 3/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
GAA P10253 2/20 0.54
ALOX12 P18054 2/20 0.54
KDM4E B2RXH2 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
USP2 O75604 2/20 0.50
POLB P06746 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30046067 1.00 TRPA1 (0.65) TRPA1TDP1TP53ALOX15HSD17B10
SCHEMBL29763149 1.00 TRPA1 (0.65) TRPA1TDP1TP53ALOX15HSD17B10
SCHEMBL6567310 0.90 TRPA1 (0.54) TRPA1TDP1TP53ALOX15HSD17B10
Sulfur Dioxide SCHEMBL20526199 0.90 TRPA1 (0.54) TRPA1TDP1TP53ALOX15HSD17B10
SCHEMBL17753391 0.90 TRPA1 (0.54) TRPA1TDP1TP53ALOX15HSD17B10
SCHEMBL18171927 0.90 TDP1 (0.58) TRPA1TDP1TP53ALOX15HSD17B10
SCHEMBL31351790 0.88 TRPA1 (0.52) TRPA1TDP1TP53ALOX15HSD17B10
SCHEMBL3484810 0.88 TRPA1 (0.52) TRPA1TDP1TP53ALOX15HSD17B10
SCHEMBL29941912 0.87 TRPA1 (0.56) TRPA1TDP1TP53ALOX15HSD17B10
SCHEMBL6847806 0.87 TRPA1 (0.56) TRPA1TDP1TP53ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0712866-B1 Polymer scale deposition preventive agent SHINETSU CHEMICAL CO (JP) 1998-07-29 EP claimed
US-5674953-A COATING SURFACES OF POLYMERIZATION APPARATUS WITH A RESIN FILM FORMED BY REACTING A DIHYDROXYBIPHENYL AND AN ALDEHYDE TO PREVENT VINYL CHLORIDE POLYMER FROM ADHERING MITSUI TOATSU CHEMICALS, INC. (JP) 1997-10-07 US claimed
EP-0712866-A1 Polymer scale deposition preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-05-22 EP claimed
EP-0462284-A1 POLYMERIZATION OF VINYL CHLORIDE MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-12-27 EP claimed
EP-4190769-B1 APPLICATION OF POLYDENTATE PHOSPHITE LIGAND IN CATALYTIC SYNTHESIS OF ADIPONITRILE ZHEJIANG NHU CO LTD (CN) 2026-02-11 EP disclosed
US-12331007-B2 Use of a multidentate phosphite ligand in the catalytic synthesis of adiponitrile ZHEJIANG NHU CO., LTD. (CN) 2025-06-17 US disclosed
US-12275695-B2 Fluid catalytic cracking of p-cresol dimer into phenolic monomers and process thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2025-04-15 US disclosed
US-20240336560-A1 Use of a Multidentate Phosphite Ligand in the Catalytic Synthesis of Adiponitrile ZHEJIANG NHU CO., LTD. (CN) 2024-10-10 US disclosed
US-20230202953-A1 FLUID CATALYTIC CRACKING OF P-CRESOL DIMER INTO PHENOLIC MONOMERS AND PROCESS THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2023-06-29 US disclosed
EP-4190769-A1 APPLICATION OF POLYDENTATE PHOSPHITE LIGAND IN CATALYTIC SYNTHESIS OF ADIPONITRILE Zhejiang University (CN) 2023-06-07 EP disclosed
WO-2023060929-A1 APPLICATION OF POLYDENTATE PHOSPHITE LIGAND IN CATALYTIC SYNTHESIS OF ADIPONITRILE 浙江大学 2023-04-20 WO disclosed
US-10686203-B2 Peptide-inorganic material composite film and manufacturing method thereof SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2020-06-16 US disclosed
EP-0760378-A1 Polymer scale deposition preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-03-05 EP disclosed
EP-0712866-A1 Polymer scale deposition preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-05-22 EP disclosed
US-5508361-A COATING THE REACTOR INTERIOR WALL AN ANTIDEPOSIT AGENT OF PHENOLIC RESIN SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-04-16 US disclosed
EP-0462284-A1 POLYMERIZATION OF VINYL CHLORIDE MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-12-27 EP disclosed
EP-0035965-B1 PROCESS FOR THE PREPARATION OF 2.2'-DIHYDROXYBIPHENYL COMPOUNDS CIBA-GEIGY AG (CH) 1983-05-18 EP disclosed
US-4380676-A Process for the production of 2,2'-dihydroxy-biphenyls CIBA-GEIGY CORPORATION (US) 1983-04-19 US disclosed
US-4312522-A A 2,2*-BISPHENOL SULFIDE, SULFOXIDE, OR SULFONE AS DEVELOPER MITSUI TOATSU CHEMICALS, INC. (JP) 1982-01-26 US disclosed
EP-0035965-A2 Process for the preparation of 2.2'-dihydroxybiphenyl compounds CIBA-GEIGY AG (CH) 1981-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12331007-B2 Use of a multidentate phosphite ligand in the catalytic synthesis of adiponitrile FABP4, LIPE, FASN TRPA1 194/4885TDP1 4423/4885TP53 1899/4885
US-20240336560-A1 Use of a Multidentate Phosphite Ligand in the Catalytic Synthesis of Adiponitrile FABP4, LIPE, FASN TRPA1 194/4885TDP1 4423/4885TP53 1899/4885
US-20230202953-A1 FLUID CATALYTIC CRACKING OF P-CRESOL DIMER INTO PHENOLIC MONOMERS AND PROCESS THEREOF CAT, MCCC2, FOS TRPA1 2424/4885TDP1 2828/4885TP53 1905/4885
US-12275695-B2 Fluid catalytic cracking of p-cresol dimer into phenolic monomers and process thereof CAT, MCCC2, FOS TRPA1 2424/4885TDP1 2828/4885TP53 1905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.