Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29370778 | 0.91 | NOTUM (0.66) | NOTUMTSHRRAB9AL3MBTL1PARP1 | |
| SCHEMBL3649822 | 0.91 | NOTUM (0.66) | NOTUMTSHRRAB9AL3MBTL1PARP1 | |
| Hydrochloric Acid SCHEMBL28144485 | 0.89 | NOTUM (0.63) | NOTUMTSHRRAB9AL3MBTL1PARP1 | |
| Hydrochloric Acid SCHEMBL16237239 | 0.89 | NOTUM (0.63) | NOTUMTSHRRAB9AL3MBTL1PARP1 | |
| Hydrochloric Acid SCHEMBL28843911 | 0.87 | NOTUM (0.61) | NOTUMTSHRRAB9AL3MBTL1PARP1 | |
| SCHEMBL29195129 | 0.85 | NOTUM (0.59) | NOTUMTSHRRAB9AL3MBTL1PARP1 | |
| Succinic Acid SCHEMBL28136128 | 0.81 | TSHR (0.56) | NOTUMTSHRRAB9AL3MBTL1PARP1 | |
| SCHEMBL27631979 | 0.79 | NOTUM (0.61) | NOTUMTSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL29453277 | 0.77 | TSHR (0.69) | NOTUMTSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL931955 | 0.77 | TSHR (0.69) | NOTUMTSHRRAB9AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146630-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-27 | — | — | US | disclosed |