Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PARP1 | P09874 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 3/20 | 0.42 |
| ▸ | CCND1 | P24385 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29370778 | 1.00 | NOTUM (0.66) | NOTUMTSHRRAB9AL3MBTL1PARP1 | |
| Hydrochloric Acid SCHEMBL16237239 | 0.98 | NOTUM (0.63) | NOTUMTSHRRAB9AL3MBTL1PARP1 | |
| Hydrochloric Acid SCHEMBL28843911 | 0.96 | NOTUM (0.61) | NOTUMTSHRRAB9AL3MBTL1PARP1 | |
| Isopropyl Alcohol SCHEMBL11540475 | 0.91 | NOTUM (0.61) | NOTUMTSHRRAB9AL3MBTL1PARP1 | |
| SCHEMBL29195129 | 0.89 | NOTUM (0.59) | NOTUMTSHRRAB9AL3MBTL1PARP1 | |
| SCHEMBL931955 | 0.85 | TSHR (0.69) | NOTUMTSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL29453277 | 0.85 | TSHR (0.69) | NOTUMTSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL2079635 | 0.84 | NOTUM (0.61) | NOTUMTSHRRAB9AL3MBTL1PARP1 | |
| Bromide SCHEMBL19150274 | 0.83 | TSHR (0.67) | NOTUMTSHRRAB9AL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL20610213 | 0.83 | TSHR (0.67) | NOTUMTSHRRAB9AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3880671-B1 | NOVEL COMPOUND AS PROTEIN KINASE INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THEREOF | HK INNO N CORP (KR) | 2025-03-12 | — | — | EP | claimed |
| US-12180185-B2 | Compound as protein kinase inhibitor, and pharmaceutical composition comprising thereof | HK INNO.N CORPORATION (KR) | 2024-12-31 | — | — | US | claimed |
| CN-119185569-A | Sustained release delivery system comprising a traceless linker | 诺华股份有限公司 | 2024-12-27 | — | — | CN | claimed |
| WO-2019189241-A1 | THERAPEUTIC AGENT FOR HEPATOCELLULAR CARCINOMA | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2019-10-03 | — | — | WO | claimed |
| CN-109789209-A | Use the method for CSF-1R inhibitors to treat ocular diseases | 诺华股份有限公司 | 2019-05-21 | — | — | CN | claimed |
| WO-2019016115-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED ARYL KETONES | BASF Agro B.V. (NL) | 2019-01-24 | — | — | WO | claimed |
| US-10174006-B2 | Topical aqueous ophthalmic compositions containing a 1H-indole-1-carboxamide derivative and use thereof for treatment of ophthalmic disease | NOVARTIS AG (CH) | 2019-01-08 | — | — | US | claimed |
| CN-109071516-A | novel compounds | 阿斯利康(瑞典)有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-105452241-B | Carboxamides derivatives of ((base of pyrimidine 4) epoxide) 1H indoles 1 and application thereof | 诺华股份有限公司 | 2018-01-05 | — | — | CN | claimed |
| CN-105073730-B | monocyclic pyridine derivatives | 卫材R&D管理有限公司 | 2017-10-13 | — | — | CN | claimed |
| WO-2012110190-A1 | NOVEL P2X7R ANTAGONISTS AND THEIR USE | AFFECTIS PHARMACEUTICALS AG (DE) | 2012-08-23 | — | — | WO | claimed |
| CN-1209359-C | Novel dihydric indole compound, their prepn. process and medicinal compsns. contg.them | SEVOIERE LAB (FR) | 2005-07-06 | — | — | CN | claimed |
| WO-2004069831-A1 | TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-08-19 | — | — | WO | claimed |
| CN-1446813-A | Novel dihydric indole compound, their prepn. process and medicinal compsns. contg.them | SEVOIERE LAB (FR) | 2003-10-08 | — | — | CN | claimed |
| CN-1333774-A | Substituted benzofuranodindoles and indenoindoles as novel potassium channel openers | AMERICAN HOME PROD (US) | 2002-01-30 | — | — | CN | claimed |
| CN-1323796-A | Novel cyclobutaneindazol carboxylamine compound, their prepn. method and pharmaceutical compositions | ADIR (FR) | 2001-11-28 | — | — | CN | claimed |
| WO-1997013767-A1 | HETEROCYCLICALLY-SUBSTITUTED 1-INDOLE CARBOXAMIDES AS CYCLO-OXYGENASE-2 INHIBITORS | CHEMISCH PHARMAZEUTISCHE FORSCHUNGSGESELLSCHAFT MBH (AT) | 1997-04-17 | — | — | WO | claimed |
| CN-1086819-A | Novel compounds having 5-hydroxytryptamine receptor antagonistic activity | SMITHKLINE BEECHAM PLC (GB) | 1994-05-18 | — | — | CN | claimed |
| US-5102901-A | 5-hydroxytrypamine receptor antaonists | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-04-07 | — | — | US | claimed |
| EP-0393766-A2 | New 3-N substituted carbamoyl-indole derivatives | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-10-24 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174006-B2 | Topical aqueous ophthalmic compositions containing a 1H-indole-1-carboxamide derivative and use thereof for treatment of ophthalmic disease | IDO1, IDO2, TPH1 | NOTUM 1543/4885TSHR 2534/4885RAB9A 2178/4885 |
| US-12180185-B2 | Compound as protein kinase inhibitor, and pharmaceutical composition comprising thereof | MAP3K20, MAP3K1, MAP3K15 | NOTUM 1104/4885TSHR 3546/4885RAB9A 1065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.