Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | DAO | P14920 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362757 | 0.91 | FLT3 (0.71) | FLT3KDM4ELMNATP53L3MBTL1 | |
| SCHEMBL118686 | 0.91 | FLT3 (0.71) | FLT3KDM4ELMNATP53L3MBTL1 | |
| Water SCHEMBL30277651 | 0.90 | FLT3 (0.69) | FLT3KDM4ELMNATP53L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30071329 | 0.90 | FLT3 (0.69) | FLT3KDM4ELMNATP53L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28280255 | 0.90 | FLT3 (0.69) | FLT3KDM4ELMNATP53L3MBTL1 | |
| Hydrochloric Acid SCHEMBL16463892 | 0.90 | FLT3 (0.69) | FLT3KDM4ELMNATP53L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30164222 | 0.90 | FLT3 (0.69) | FLT3KDM4ELMNATP53L3MBTL1 | |
| Bromide SCHEMBL6056708 | 0.90 | FLT3 (0.69) | FLT3KDM4ELMNATP53L3MBTL1 | |
| Hydrochloric Acid SCHEMBL20569802 | 0.90 | FLT3 (0.69) | FLT3KDM4ELMNATP53L3MBTL1 | |
| SCHEMBL8608084 | 0.85 | KDM4E (0.59) | FLT3KDM4ELMNATP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146630-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-27 | — | — | US | disclosed |