Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | DAO | P14920 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362757 | 1.00 | FLT3 (0.71) | FLT3KDM4EHSD17B10MAPTDAO | |
| Hydrochloric Acid SCHEMBL28280255 | 0.98 | FLT3 (0.69) | FLT3KDM4EHSD17B10MAPTDAO | |
| Water SCHEMBL30277651 | 0.98 | FLT3 (0.69) | FLT3KDM4EHSD17B10MAPTDAO | |
| Hydrochloric Acid SCHEMBL20569802 | 0.98 | FLT3 (0.69) | FLT3KDM4EHSD17B10MAPTDAO | |
| Bromide SCHEMBL6056708 | 0.98 | FLT3 (0.69) | FLT3KDM4EHSD17B10MAPTDAO | |
| Hydrochloric Acid SCHEMBL30164222 | 0.98 | FLT3 (0.69) | FLT3KDM4EHSD17B10MAPTDAO | |
| Hydrochloric Acid SCHEMBL30071329 | 0.98 | FLT3 (0.69) | FLT3KDM4EHSD17B10MAPTDAO | |
| Hydrochloric Acid SCHEMBL16463892 | 0.98 | FLT3 (0.69) | FLT3KDM4EHSD17B10MAPTDAO | |
| Pyrrole SCHEMBL7648947 | 0.91 | KDM4E (0.61) | FLT3KDM4EHSD17B10MAPTDAO | |
| Isopropyl Alcohol SCHEMBL11540479 | 0.91 | FLT3 (0.61) | FLT3KDM4EHSD17B10MAPTDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2527 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122056281-A | Application of indoleamide compound as linker for mediating interaction of ubiquitin ligase and effector protein | 中国农业大学 | 2026-05-19 | — | — | CN | claimed |
| US-12465588-B2 | Indole carboxamide derivative and pharmaceutical composition containing same | KUKJE PHARMA CO., LTD. (KR) | 2025-11-11 | — | — | US | claimed |
| EP-4561704-A2 | USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER | The University Of Vermont (US) | 2025-06-04 | — | — | EP | claimed |
| CN-116396284-B | Benzo-seven-membered nitrogen-oxygen heterocyclic indole-2-carboxamide derivative, preparation method and application thereof | 宁夏医科大学 | 2025-03-25 | — | — | CN | claimed |
| US-20250082652-A1 | SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES | UNIVERSITÄT ZU KÖLN (DE) | 2025-03-13 | — | — | US | claimed |
| CN-114302874-B | Indole carboxamide derivatives and pharmaceutical compositions containing the same | 国际药品株式会社 | 2025-02-25 | — | — | CN | claimed |
| US-20250032629-A1 | NOVEL NUCLEOLIN-BINDING PEPTIDE AND USE THEREOF | ANYGEN CO., LTD. (KR) | 2025-01-30 | — | — | US | claimed |
| CN-119306650-A | Preparation method of indole carboxamide compound | 西安睿舒维生物医药科技有限公司 | 2025-01-14 | — | — | CN | claimed |
| US-12180185-B2 | Compound as protein kinase inhibitor, and pharmaceutical composition comprising thereof | HK INNO.N CORPORATION (KR) | 2024-12-31 | — | — | US | claimed |
| CN-119080755-A | 1-Methyl-6-chromene ketoindole-2-carboxamide compound, and preparation method and application thereof | 河南省锐达医药科技有限公司 | 2024-12-06 | — | — | CN | claimed |
| EP-0546181-A1 | INDOLE DERIVATIVES AND THEIR USE AS SEROTONIN ANTAGONISTS | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-06-16 | — | — | EP | claimed |
| EP-0497835-A1 | METHOD FOR TREATING HIV AND OTHER RETROVIRUSES AND COMPOUNDS USEFUL THEREFOR | THE UPJOHN COMPANY (US) | 1992-08-12 | — | — | EP | claimed |
| US-5102901-A | 5-hydroxytrypamine receptor antaonists | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-04-07 | — | — | US | claimed |
| WO-1991006561-A1 | METHOD FOR TREATING HIV AND OTHER RETROVIRUSES AND COMPOUNDS USEFUL THEREFOR | THE UPJOHN COMPANY (US) | 1991-05-16 | — | — | WO | claimed |
| EP-0213984-B1 | INDOLE CARBOXAMIDE DERIVATIVES, THEIR SALTS, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1991-01-09 | — | — | EP | claimed |
| EP-0393766-A2 | New 3-N substituted carbamoyl-indole derivatives | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-10-24 | — | — | EP | claimed |
| EP-0343961-A2 | Aryl- and heteroaryl piperazinyl carboxamides having central nervous system activity | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-11-29 | — | — | EP | claimed |
| US-4868200-A | LEUKOTRIENES, LIPOXYGENASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | claimed |
| US-4791109-A | Novel indole carboxamides | ROUSSEL UCLAF (FR) | 1988-12-13 | — | — | US | claimed |
| EP-0186367-A2 | Acidic indole compounds and their use as antiallergy agents | WARNER-LAMBERT COMPANY (US) | 1986-07-02 | — | — | EP | claimed |