Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SDCBP | O00560 | 1/20 | 0.46 |
| ▸ | SDC2 | P34741 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286277 | 0.89 | FFAR1 (0.65) | ALDH1A1L3MBTL1FFAR1HSD17B10KMT2A | |
| Hydrochloric Acid SCHEMBL11623652 | 0.87 | FFAR1 (0.63) | ALDH1A1L3MBTL1FFAR1HSD17B10KMT2A | |
| SCHEMBL11539694 | 0.86 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1TDP1HSD17B10KMT2A | |
| SCHEMBL21451083 | 0.86 | ALDH1A1 (0.89) | ALDH1A1L3MBTL1TDP1FFAR1HSD17B10 | |
| SCHEMBL11539899 | 0.84 | FFAR1 (0.59) | ALDH1A1L3MBTL1FFAR1HSD17B10KMT2A | |
| SCHEMBL7409066 | 0.80 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1TDP1HSD17B10KMT2A | |
| SCHEMBL8000250 | 0.79 | ALDH1A1 (0.75) | ALDH1A1FFAR1HSD17B10GAAMAPK1 | |
| SCHEMBL11986376 | 0.77 | ALDH1A1 (0.72) | ALDH1A1FFAR1HSD17B10KMT2ARAB9A | |
| SCHEMBL4255888 | 0.77 | ALDH1A1 (0.72) | ALDH1A1FFAR1HSD17B10KMT2ARAB9A | |
| SCHEMBL7298915 | 0.76 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1TDP1HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156011-A | TREATMENT OF CARDIOVASCULAR DISORDERS | SOCIETE ANONYME DITE: LABORATOIRE L. LAFON (FR) | 1979-05-22 | — | — | US | disclosed |