Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.38 |
| ▸ | CA7 | P43166 | 13/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 13/20 | 0.38 |
| ▸ | CA1 | P00915 | 12/20 | 0.38 |
| ▸ | CA12 | O43570 | 12/20 | 0.37 |
| ▸ | CA4 | P22748 | 12/20 | 0.37 |
| ▸ | CA6 | P23280 | 11/20 | 0.37 |
| ▸ | CA9 | Q16790 | 11/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 11/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 11/20 | 0.37 |
| ▸ | CA3 | P07451 | 10/20 | 0.37 |
| ▸ | CA5A | P35218 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541795 | 0.94 | CA2 (0.37) | CA2CA7CA13CA1CA12 | |
| Hydrochloric Acid SCHEMBL11540279 | 0.82 | CA2 (0.40) | CA2CA7CA13CA1CA12 | |
| SCHEMBL11543687 | 0.81 | CA2 (0.41) | CA2CA7CA13CA1CA12 | |
| SCHEMBL11540598 | 0.81 | CA2 (0.39) | CA2CA7CA13CA1CA12 | |
| SCHEMBL11542286 | 0.79 | CA1 (0.39) | CA2CA7CA13CA1CA12 | |
| SCHEMBL11540030 | 0.78 | KDM4E (0.55) | CA2CA7CA13CA1CA12 | |
| SCHEMBL2880825 | 0.76 | CA2 (0.44) | CA2CA7CA13CA1CA12 | |
| SCHEMBL11541800 | 0.74 | CA2 (0.38) | CA2CA7CA13CA1CA12 | |
| SCHEMBL7291013 | 0.72 | KDM4E (0.53) | CA2CA7CA13CA1CA12 | |
| SCHEMBL11788977 | 0.71 | CISD1 (0.53) | CA2CA7CA13CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176190-A | Diuretic and saliuretic sulphamoylbenzoic acids | CIBA-GEIGY CORPORATION (US) | 1979-11-27 | — | — | US | disclosed |