Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3 | P19429 | 1/20 | 0.33 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351979 | 0.68 | TNNI3 (0.61) | TNNI3TNNT2TNNC1ACHEBCHE | |
| SCHEMBL29798812 | 0.68 | TNNI3 (0.61) | TNNI3TNNT2TNNC1ACHEBCHE | |
| SCHEMBL11536506 | 0.64 | ACHE (0.34) | ACHEBCHE | |
| SCHEMBL60689 | 0.56 | — | — | |
| SCHEMBL28644224 | 0.54 | CYP2A6 (0.47) | ACHEATMMEN1KMT2A | |
| SCHEMBL30505849 | 0.54 | CYP2A6 (0.47) | ACHEATMMEN1KMT2A | |
| Benzene SCHEMBL7937270 | 0.54 | CYP2A6 (0.47) | MEN1RAB9AKMT2A | |
| SCHEMBL29649306 | 0.54 | CYP2A6 (0.47) | ACHEATMMEN1KMT2A | |
| SCHEMBL30253511 | 0.54 | CYP2A6 (0.47) | ACHEATMMEN1KMT2A | |
| SCHEMBL27384288 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163745-A | ANTIDIABETIC, HYPOGLYCEMIC | PFIZER INC. (US) | 1979-08-07 | — | — | US | disclosed |