Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541925 | 0.95 | MAPKAPK2 (0.58) | ALDH1A1GAASMN1; SMN2KDM4EHTT | |
| SCHEMBL10670035 | 0.91 | MAPKAPK2 (0.53) | ALDH1A1GAASMN1; SMN2KDM4EHTT | |
| SCHEMBL11544358 | 0.91 | MAPKAPK2 (0.53) | ALDH1A1GAASMN1; SMN2KDM4EHTT | |
| SCHEMBL11543575 | 0.91 | MAPKAPK2 (0.53) | ALDH1A1GAASMN1; SMN2KDM4EHTT | |
| SCHEMBL11545265 | 0.91 | MAPKAPK2 (0.51) | ALDH1A1GAASMN1; SMN2KDM4EHTT | |
| SCHEMBL11542427 | 0.89 | MAPT (0.51) | ALDH1A1GAASMN1; SMN2KDM4EHTT | |
| SCHEMBL11541437 | 0.89 | GAA (0.49) | ALDH1A1GAASMN1; SMN2KDM4EHTT | |
| SCHEMBL11541399 | 0.89 | MAPKAPK2 (0.51) | ALDH1A1GAASMN1; SMN2KDM4EHTT | |
| SCHEMBL11544220 | 0.88 | KMT2A (0.53) | ALDH1A1GAASMN1; SMN2KDM4EHTT | |
| SCHEMBL11542321 | 0.87 | L3MBTL1 (0.50) | ALDH1A1GAAKDM4EMAPKAPK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |