Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | YAP1 | P46937 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541925 | 0.91 | MAPKAPK2 (0.58) | KMT2AMAPKAPK2GAAALDH1A1MAPK1 | |
| SCHEMBL10670035 | 0.88 | MAPKAPK2 (0.53) | KMT2AMAPKAPK2GAAALDH1A1MAPK1 | |
| SCHEMBL11544358 | 0.88 | MAPKAPK2 (0.53) | KMT2AMAPKAPK2GAAALDH1A1MAPK1 | |
| SCHEMBL11543575 | 0.88 | MAPKAPK2 (0.53) | KMT2AMAPKAPK2GAAALDH1A1MAPK1 | |
| SCHEMBL11540780 | 0.88 | ALDH1A1 (0.57) | KMT2AMAPKAPK2GAAALDH1A1MAPK1 | |
| SCHEMBL11542427 | 0.85 | MAPT (0.51) | KMT2AMAPKAPK2GAAALDH1A1MAPK1 | |
| SCHEMBL11541399 | 0.85 | MAPKAPK2 (0.51) | KMT2AMAPKAPK2GAAALDH1A1MAPK1 | |
| SCHEMBL11507819 | 0.84 | RAD52 (0.58) | KMT2AMAPKAPK2GAAALDH1A1CYP1A2 | |
| SCHEMBL11523029 | 0.83 | HRH3 (0.50) | KMT2AMAPKAPK2GAAALDH1A1MAPK1 | |
| SCHEMBL11507910 | 0.83 | ALDH1A1 (0.52) | KMT2AGAAALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |